The McDevitt laboratory is focused on the engineering of innovative technologies to translate the regenerative potential of stem cells into effective cellular and molecular therapies for the treatment of degenerative diseases and traumatic  injuries.  By developing controlled systems approaches to engineer the microenvironment of stem cells, we aspire to improve the efficiency and yield of directed stem cell differentiation strategies.

We also seek to develop novel regenerative molecular therapies based on the morphogens produced by stem cells.  Efficient scalable bioprocesses will require the development of enabling tools and technologies to facilitate the production of stem cell technologies. The combination of directed stem cell differentiation and derivation of stem cell biotherapeutics will yield fresh insights into stem cell biology and facilitate new regenerative therapies.

Research

The McDevitt laboratory is focused on the engineering of innovative approaches to transform the potential of stem cells into effective molecular and cellular regenerative therapies and in vitro diagnostic technologies.  By developing controlled systems approaches to engineer the microenvironment of stem cells, we aspire to improve the efficiency and reproducibility of directed stem cell differentiation strategies. 

We also seek to develop novel regenerative molecular therapies based on the morphogens produced by stem cells. Successful translation of stem cell technologies will ultimately require scalable bioprocesses capable of yielding the quantities of cells and derivatives thought to be necessary for therapeutic and diagnostic applications.

The combination of directed stem cell differentiation and derivation of stem cell biotherapeutics will yield fresh insights into stem cell biology, facilitate new regenerative therapies, and create novel cell diagnostic platforms.

Related Websites

Stem Cell Engineering Center Website

Stem Cell Biomanufacturing IGERT Training program for graduate students